SCHEMBL11602007

SCHEMBL11602007

CCCCCC(O)CCCCS(=O)(=O)NCCCCCCC(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.65
FFAR1 O14842 2/20 0.65
FAAH O00519 2/20 0.51
GPR84 Q9NQS5 6/20 0.50
RELA Q04206 4/20 0.48
TBXA2R P21731 1/20 0.47
PTGFR P43088 1/20 0.47
PTGER2 P43116 1/20 0.47
PPARG P37231 3/20 0.46
PPARD Q03181 3/20 0.46
PPARA Q07869 3/20 0.46
TSHR P16473 2/20 0.46
HDAC11 Q96DB2 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 1/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
SLC22A8 Q8TCC7 1/20 0.46
TLR2 O60603 1/20 0.46
MEN1 O00255 1/20 0.46
ESR1 P03372 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11601260 1.00 FFAR4 (0.65) FFAR4FFAR1FAAHGPR84RELA
SCHEMBL11601441 0.89 RELA (0.51) FFAR4FFAR1FAAHGPR84RELA
SCHEMBL11601862 0.88 FFAR4 (0.48) FFAR4FFAR1FAAHTBXA2RALDH1A1
SCHEMBL11601964 0.87 FFAR4 (0.47) FFAR4FFAR1FAAHTBXA2RALDH1A1
SCHEMBL11603766 0.87 CA12 (0.55) FFAR4FFAR1FAAHGPR84RELA
SCHEMBL11728379 0.87 FFAR4 (0.48) FFAR4FFAR1FAAHGPR84RELA
SCHEMBL11602334 0.86 ACE2 (0.49) FFAR4FFAR1FAAHGPR84RELA
SCHEMBL11731423 0.86 FFAR4 (0.47) FFAR4FFAR1FAAHGPR84RELA
SCHEMBL11734582 0.85 FFAR4 (0.46) FFAR4FFAR1FAAHGPR84RELA
SCHEMBL11728625 0.85 FFAR4 (0.44) FFAR4FFAR1FAAHGPR84RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4033996-A RENAL VASODILATORS, ANTITHROMBOSIS, GROWTH HORMONE RELEASING MERCK & CO., INC. (US) 1977-07-05 US claimed
US-4091107-A RENAL VASODILATORS, ANTICLOTTING AGENTS, GROWTH HORMONE RELEASE, REGULATORS OF IMMUNE RESPONSE MERCK & CO., INC. (US) 1978-05-23 US disclosed
US-4033996-A RENAL VASODILATORS, ANTITHROMBOSIS, GROWTH HORMONE RELEASING MERCK & CO., INC. (US) 1977-07-05 US disclosed