Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 2/20 | 0.60 |
| ▸ | SELE | P16581 | 2/20 | 0.60 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.57 |
| ▸ | SELL | P14151 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | PPARD | Q03181 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11627789 | 0.88 | CSNK2A1 (0.54) | SELPSELEHPSENR1H4SELL | |
| SCHEMBL4515437 | 0.87 | HPSE (0.57) | SELPSELEHPSENR1H4SELL | |
| Phenylurea SCHEMBL5852221 | 0.86 | AKR1B1 (0.63) | HPSENR1H4GAAMAPTGFER | |
| SCHEMBL11509798 | 0.85 | NOS3 (0.48) | SELPSELEHPSENR1H4GAA | |
| SCHEMBL4505211 | 0.84 | GAA (0.55) | GAAMAPTGFERITGB3ITGA2B | |
| SCHEMBL11359247 | 0.83 | SELP (0.65) | SELPSELEHPSENR1H4SELL | |
| SCHEMBL30557308 | 0.83 | HPSE (0.78) | SELPSELEHPSENR1H4SELL | |
| SCHEMBL3976944 | 0.83 | NR1H4 (0.61) | SELPSELEHPSENR1H4SELL | |
| SCHEMBL6136003 | 0.83 | HPSE (0.78) | SELPSELEHPSENR1H4SELL | |
| SCHEMBL27951813 | 0.83 | NR3C2 (0.59) | GAAMAPTGFERITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1075717-A | Benzodiazepine * derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1993-09-01 | — | — | CN | disclosed |
| US-4091227-A | ANTIBACTERIAL AGENTS | SMITHKLINE CORPORATION (US) | 1978-05-23 | — | — | US | disclosed |
| US-4067977-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4067978-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4067976-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4007173-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |