Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PLD2 | O14939 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | C5 | P01031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600056 | 0.89 | LTA4H (0.56) | ESR1ESR2LTA4HMEN1ALDH1A1 | |
| SCHEMBL11600463 | 0.88 | HRH3 (0.51) | ESR1ESR2GCGRLTA4H | |
| SCHEMBL11600610 | 0.87 | LTA4H (0.44) | ESR1ESR2GCGRLTA4H | |
| SCHEMBL11601880 | 0.85 | ESR1 (0.59) | ESR1ESR2GCGRLTA4HDRD2 | |
| SCHEMBL11599709 | 0.85 | GCGR (0.49) | ESR1ESR2GCGRLTA4HKCNH2 | |
| SCHEMBL11599995 | 0.83 | LTA4H (0.53) | ESR1ESR2LTA4HALDH1A1 | |
| SCHEMBL11602278 | 0.83 | LTA4H (0.51) | ESR1ESR2GCGRLTA4HALDH1A1 | |
| SCHEMBL11600553 | 0.83 | ESR1 (0.55) | ESR1ESR2LTA4HALDH1A1 | |
| SCHEMBL11601598 | 0.82 | KDM4E (0.53) | ESR1ESR2LTA4HALDH1A1 | |
| SCHEMBL11600588 | 0.81 | ESR1 (0.64) | ESR1ESR2MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |