Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 12/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600553 | 0.92 | ESR1 (0.55) | KDM4ELTA4HESR1ESR2PSMB1 | |
| SCHEMBL11599995 | 0.89 | LTA4H (0.53) | KDM4ELTA4HESR1ESR2PSMB1 | |
| SCHEMBL11552007 | 0.87 | KDM4E (0.53) | KDM4ELTA4HESR1ESR2PSMB1 | |
| SCHEMBL11600056 | 0.84 | LTA4H (0.56) | LTA4HESR1ESR2ALDH1A1 | |
| SCHEMBL11600730 | 0.84 | UBE2N (0.51) | KDM4ELTA4HESR1ESR2PSMB1 | |
| SCHEMBL11600463 | 0.84 | HRH3 (0.51) | LTA4HESR1ESR2PSMB1PSMB5 | |
| SCHEMBL11601880 | 0.82 | ESR1 (0.59) | LTA4HESR1ESR2PSMB1PSMB5 | |
| SCHEMBL11601667 | 0.82 | ESR1 (0.51) | LTA4HESR1ESR2ALDH1A1 | |
| SCHEMBL11600683 | 0.81 | ESR1 (0.60) | KDM4ELTA4HESR1ESR2ALDH1A1 | |
| SCHEMBL11602278 | 0.80 | LTA4H (0.51) | KDM4ELTA4HESR1ESR2PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |