Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 7/20 | 0.54 |
| ▸ | MAOA | P21397 | 6/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840252 | 0.90 | MAOB (0.57) | ALDH1A1MAOBMAOAMMP2HTT | |
| SCHEMBL10050946 | 0.81 | MAOB (0.56) | ALDH1A1MAOBMAOAFFAR1 | |
| SCHEMBL11606889 | 0.79 | HTT (0.59) | ALDH1A1MAOBMAOAMMP2HTT | |
| SCHEMBL416482 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1015539 | 0.79 | MAOB (0.56) | ALDH1A1MAOBMAOACYP19A1SMN1; SMN2 | |
| SCHEMBL1932191 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL414617 | 0.77 | ALDH1A1 (0.70) | ALDH1A1HTTL3MBTL1NPC1RAB9A | |
| SCHEMBL414504 | 0.77 | ALDH1A1 (0.70) | ALDH1A1HTTSMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL417732 | 0.77 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL5209754 | 0.77 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086240-A | 1-Thiazolyl-5-phenoxy and phenylthioalkanoyloxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |
| US-4053480-A | 1-THIADIAZOLYL-5-PHENOXY- AND PHENYLTHIOALKANOYLOXY IMIDAZOLIDINONES | VELSICOL CHEMICAL CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |