Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4995027 | 0.95 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ECYP1A2CYP3A4 | |
| SCHEMBL21102358 | 0.93 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ECYP1A2CYP3A4 | |
| SCHEMBL21102172 | 0.93 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ECYP1A2CYP3A4 | |
| SCHEMBL909499 | 0.89 | HPGD (0.60) | ALDH1A1HPGDKDM4ECYP1A2CYP3A4 | |
| SCHEMBL17131550 | 0.85 | HPGD (0.53) | ALDH1A1HPGDKDM4ECYP1A2CYP3A4 | |
| SCHEMBL20578188 | 0.84 | HPGD (0.51) | ALDH1A1HPGDKDM4ECYP1A2CYP3A4 | |
| SCHEMBL416482 | 0.83 | ALDH1A1 (0.72) | ALDH1A1CYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL1932191 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ECYP1A2CYP3A4 | |
| SCHEMBL2213968 | 0.82 | ALDH1A1 (0.66) | ALDH1A1HPGDNPC1RAB9AL3MBTL1 | |
| SCHEMBL9775156 | 0.82 | RAB9A (0.70) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634948-B1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | INST NAT SANTE RECH MED (FR) | 2025-09-17 | — | — | EP | disclosed |
| EP-3634949-B1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | INST NAT SANTE RECH MED (FR) | 2025-03-19 | — | — | EP | disclosed |
| US-11795144-B2 | Inhibitors of RAC1 and uses thereof for treating cancers | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-10-24 | — | — | US | disclosed |
| US-11607419-B2 | Inhibitors of RAC1 and uses thereof for inducing bronchodilatation | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2023-03-21 | — | — | US | disclosed |
| WO-2018224563-A9 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2021-04-22 | — | — | WO | disclosed |
| US-20210077508-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | NANTES UNIVERSITE (FR) | 2021-03-18 | — | — | US | disclosed |
| EP-3634949-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2020-04-15 | — | — | EP | disclosed |
| EP-3634948-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | Institut National de la Sante et de la Recherche Medicale (INSERM) (FR) | 2020-04-15 | — | — | EP | disclosed |
| US-20200095199-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | NANTES UNIVERSITE (FR) | 2020-03-26 | — | — | US | disclosed |
| EP-2046736-B1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2019-06-12 | — | — | EP | disclosed |
| WO-2018224560-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-12-13 | — | — | WO | disclosed |
| WO-2018224563-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-12-13 | — | — | WO | disclosed |
| EP-3412651-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-12-12 | — | — | EP | disclosed |
| EP-3412652-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-12-12 | — | — | EP | disclosed |
| US-20120022054-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2012-01-26 | — | — | US | disclosed |
| EP-2376431-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066847-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | CELLVIR (FR) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795144-B2 | Inhibitors of RAC1 and uses thereof for treating cancers | RAC1, KRAS, CYRIB | ALDH1A1 2069/4885HPGD 1309/4885KDM4E 4341/4885 |
| US-11607419-B2 | Inhibitors of RAC1 and uses thereof for inducing bronchodilatation | RAC1, CYRIB, ARHGDIB | ALDH1A1 2264/4885HPGD 550/4885KDM4E 4687/4885 |
| US-20120022054-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | HAVCR2, MAVS, EIF2AK2 | ALDH1A1 455/4885HPGD 2716/4885KDM4E 674/4885 |
| US-20210077508-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION | RAC1, CYRIB, ARHGDIB | ALDH1A1 2264/4885HPGD 550/4885KDM4E 4687/4885 |
| US-20200095199-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | RAC1, KRAS, CYRIB | ALDH1A1 2069/4885HPGD 1309/4885KDM4E 4341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.