Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599716 | 0.81 | ALDH1A1 (0.40) | FABP3FABP4FABP5ALDH1A1RORC | |
| SCHEMBL11599650 | 0.80 | ALDH1A1 (0.51) | NPC1HPGDTP53RAB9AMAPT | |
| SCHEMBL11599360 | 0.73 | AKR1C3 (0.41) | HPGDMAPTHTTALDH1A1 | |
| SCHEMBL11602662 | 0.72 | KMT2A (0.43) | NPC1HPGDTP53RAB9AMAPT | |
| SCHEMBL11599859 | 0.72 | MAPT (0.50) | FABP3FABP4FABP5NPC1HPGD | |
| SCHEMBL11600648 | 0.72 | ALDH1A1 (0.45) | NPC1HPGDRAB9AMAPTHTT | |
| SCHEMBL11623727 | 0.71 | CNR2 (0.50) | FABP3FABP4FABP5NPC1HPGD | |
| SCHEMBL11599769 | 0.70 | HTT (0.34) | NPC1HPGDRAB9AMAPTHTT | |
| SCHEMBL322168 | 0.69 | CTSD (0.62) | NPC1ALOX15HSD17B10RAB9ACNR2 | |
| SCHEMBL29658169 | 0.69 | CTSD (0.62) | NPC1ALOX15HSD17B10RAB9ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |