Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3161785 | 0.81 | — | — | |
| SCHEMBL17367646 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRBSMN1; SMN2LMNA | |
| Hexane SCHEMBL11409372 | 0.71 | — | — | |
| Heptane SCHEMBL11409882 | 0.67 | — | — | |
| Nonane SCHEMBL11414685 | 0.67 | TSHR (0.73) | ALDH1A1TSHRTHRBTP53SMN1; SMN2 | |
| Octane SCHEMBL11411019 | 0.67 | TSHR (0.73) | ALDH1A1TSHRTHRBTP53SMN1; SMN2 | |
| Decane SCHEMBL11410043 | 0.67 | TSHR (0.73) | ALDH1A1TSHRTHRBTP53SMN1; SMN2 | |
| SCHEMBL5932738 | 0.66 | — | — | |
| Pentane SCHEMBL11410718 | 0.64 | — | — | |
| SCHEMBL1042256 | 0.64 | TSHR (0.53) | ALDH1A1TSHRTHRBLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101571-A | REACTING SULFAMIC ACIDS WITH PHOSGENE | BASF AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |