Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601305 | 0.87 | DNM1 (0.49) | L3MBTL1FFAR4FFAR1KDM4EDUSP3 | |
| SCHEMBL4964157 | 0.85 | FFAR4 (0.69) | FFAR4FFAR1FAAHPPARGGPR84 | |
| SCHEMBL11602010 | 0.85 | FFAR4 (0.69) | FFAR4FFAR1FAAHPPARGGPR84 | |
| SCHEMBL11602008 | 0.85 | FFAR4 (0.69) | FFAR4FFAR1FAAHPPARGGPR84 | |
| SCHEMBL11601442 | 0.85 | FFAR4 (0.51) | FFAR4FFAR1FAAHGPR84MEN1 | |
| SCHEMBL11601264 | 0.85 | FFAR4 (0.69) | FFAR4FFAR1FAAHPPARGGPR84 | |
| SCHEMBL8620968 | 0.84 | FFAR4 (0.65) | L3MBTL1FFAR4FFAR1FAAHPPARG | |
| SCHEMBL15153576 | 0.84 | FFAR4 (0.65) | L3MBTL1FFAR4FFAR1FAAHPPARG | |
| SCHEMBL8586140 | 0.84 | FFAR4 (0.65) | L3MBTL1FFAR4FFAR1FAAHPPARG | |
| SCHEMBL293897 | 0.84 | FFAR4 (0.65) | L3MBTL1FFAR4FFAR1FAAHPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091107-A | RENAL VASODILATORS, ANTICLOTTING AGENTS, GROWTH HORMONE RELEASE, REGULATORS OF IMMUNE RESPONSE | MERCK & CO., INC. (US) | 1978-05-23 | — | — | US | disclosed |
| US-4033996-A | RENAL VASODILATORS, ANTITHROMBOSIS, GROWTH HORMONE RELEASING | MERCK & CO., INC. (US) | 1977-07-05 | — | — | US | disclosed |