Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602358 | 0.78 | KDM4C (0.52) | KDM4CHCAR2TSHR | |
| SCHEMBL7708458 | 0.74 | RECQL (0.51) | KDM4CLTA4HBRD4 | |
| SCHEMBL2235642 | 0.70 | KDM4C (0.44) | KDM4CLTA4HTSHRGPR84 | |
| SCHEMBL5206240 | 0.67 | NOS1 (0.45) | KDM4CLTA4HBRD4 | |
| SCHEMBL11603664 | 0.67 | KDM4C (0.38) | KDM4CLTA4HBRD4TSHR | |
| SCHEMBL17959988 | 0.62 | LTA4H (0.51) | KDM4CLTA4HBRD4TSHR | |
| SCHEMBL3061823 | 0.62 | GAA (0.50) | DAOLTA4HBRD4TSHR | |
| SCHEMBL31118175 | 0.62 | KDM4E (0.40) | DAOTSHR | |
| SCHEMBL702582 | 0.61 | PARP10 (0.58) | LTA4HTSHR | |
| Ammonia Solution, Strong SCHEMBL4266595 | 0.60 | PARP10 (0.56) | LTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092313-A | FROM 2,4-DICHLORO-5-FLUOROPYRIMIDINE AND AN ALCOHOLATE OR A PHENOLATE TO PRODUCE 2,4-DISUBSTITUTED DERIVATIVE, HYDROLYSIS | TAISHO PHARMACEUTICAL COMPANY LIMITED (JA) | 1978-05-30 | — | — | US | disclosed |
| US-4080455-A | ANTITUMOR | TAISHO PHARMACEUTICAL COMPANY LIMITED (JA) | 1978-03-21 | — | — | US | disclosed |