SCHEMBL1160403

SCHEMBL1160403

CCCCCc1cc(CCCCC)c(O)c(CCCCC)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 8/20 0.63
CYP3A4 P08684 2/20 0.63
ALOX5 P09917 4/20 0.53
ESR1 P03372 2/20 0.50
ADRA2A P08913 2/20 0.50
ADORA3 P0DMS8 2/20 0.50
TACR2 P21452 2/20 0.50
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 2/20 0.50
SLC6A3 Q01959 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
SHBG P04278 1/20 0.50
TP53 P04637 1/20 0.50
HSPD1 P10809 1/20 0.50
ADRB3 P13945 1/20 0.50
HTR2C P28335 1/20 0.50
HSPE1 P61604 1/20 0.50
HIF1A Q16665 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15867510 0.98 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL201605 0.98 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL199837 0.98 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL10885674 0.98 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL11806112 0.98 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL199535 0.98 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL11801101 0.98 PTGS2 (0.61) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL4969327 0.98 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL202874 0.98 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL15867513 0.98 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105142605-B 1, 2-alkane polyol-containing composition 大阪有机化学工业株式会社 2018-06-08 CN disclosed
US-9795549-B2 1,2-alkane polyol-containing composition OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2017-10-24 US disclosed
US-20160045414-A1 1,2-ALKANE POLYOL-CONTAINING COMPOSITION OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2016-02-18 US disclosed
EP-2985017-A1 1,2-ALKANE POLYOL-CONTAINING COMPOSITION Osaka Organic Chemical Ind., Ltd. (JP) 2016-02-17 EP disclosed
CN-105142605-A 1, 2-alkane polyol-containing composition OSAKA ORGANIC CHEM IND 2015-12-09 CN disclosed
US-8008383-B2 Liquid amylaryl phosphite compositions CHEMTURA CORPORATION (US) 2011-08-30 US disclosed
US-7947769-B2 Liquid amylaryl phosphite compositions and alkylate compositions for manufacturing same CHEMTURA CORPORATION (US) 2011-05-24 US disclosed
WO-2011014209-A1 LIQUID AMYLARYL PHOSPHITE COMPOSITIONS CHEMTURA CORPORATION (US) 2011-02-03 WO disclosed
US-20100069542-A1 LIQUID AMYLARYL PHOSPHITE COMPOSITIONS AND ALKYLATE COMPOSITIONS FOR MANUFACTURING SAME CHEMTURA CORPORATION (US) 2010-03-18 US disclosed
US-20090326112-A1 LIQUID AMYLARYL PHOSPHITE COMPOSITIONS CHEMTURA CORPORATION (US) 2009-12-31 US disclosed
US-3959207-A PHENOLIC COMPOUNDS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-05-25 US disclosed