Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.52 |
| ▸ | CDK4 | P11802 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657351 | 0.94 | MAPT (0.58) | MAPTHTTSMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL11604613 | 0.92 | MAPT (0.50) | MAPTHTTSMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL11603098 | 0.90 | PLA2G4B (0.62) | MAPTHTTSMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL11608439 | 0.87 | ADRB1 (0.52) | MAPTHTTSMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL11609274 | 0.87 | PLA2G4B (0.60) | MAPTHTTSMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL11604605 | 0.87 | MAPT (0.52) | MAPTHTTADRB3CDK4KMT2A | |
| SCHEMBL11608113 | 0.87 | CDK4 (0.51) | MAPTHTTSMN1; SMN2CDK4KMT2A | |
| SCHEMBL2721052 | 0.86 | MAPT (0.67) | MAPTHTTSMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL11605988 | 0.84 | MAPT (0.65) | MAPTHTTSMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL11608425 | 0.84 | BACE1 (0.59) | MAPTHTTSMN1; SMN2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072654-A | FOR DIENE-POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-02-07 | — | — | US | claimed |
| US-4072654-A | FOR DIENE-POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-02-07 | — | — | US | disclosed |