Sugi Predict

Sugi Predict / Compounds / SCHEMBL2721052

SCHEMBL2721052

SCHEMBL2721052

OC(COc1ccc(Nc2ccccc2)cc1)COc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.67
▸ HTT P42858 1/20 0.67
▸ SMN1; SMN2 Q16637 1/20 0.67
▸ ADRB1 P08588 2/20 0.61
▸ ADRB3 P13945 2/20 0.61
▸ ALDH1A1 P00352 2/20 0.59
▸ MEN1 O00255 1/20 0.59
▸ PTPN7 P35236 1/20 0.59
▸ KMT2A Q03164 1/20 0.59
▸ PTPN12 Q05209 1/20 0.59
▸ CDK4 P11802 6/20 0.57
▸ CYP2D6 P10635 2/20 0.54
▸ CDK2 P24941 4/20 0.52
▸ ADRB2 P07550 1/20 0.51
▸ LMNA P02545 1/20 0.48
▸ L3MBTL1 Q9Y468 2/20 0.48
▸ ALOX15 P16050 1/20 0.48
▸ TSHR P16473 1/20 0.48
▸ ALOX12 P18054 1/20 0.48
▸ PTGS1 P23219 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11605988 0.98 MAPT (0.65) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11607511 0.92 MAPT (0.58) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11608477 0.91 MAPT (0.56) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11608123 0.90 MAPT (0.59) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11608128 0.90 MAPT (0.59) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11602854 0.89 MAPT (0.88) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11657351 0.89 MAPT (0.58) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11609943 0.87 ADRB1 (0.76) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11604202 0.86 MAPT (0.55) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11649114 0.86 MAPT (0.56) MAPTHTTSMN1; SMN2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110172136-B High-temperature yellowing resistant epoxy resin composition and preparation method thereof 深圳市安品有机硅材料有限公司 2022-03-25 — — CN claimed
CN-115536954-A Composite material, preparation method thereof and washing machine enclosure frame 海信冰箱有限公司 2022-12-30 — — CN disclosed
CN-110172136-B High-temperature yellowing resistant epoxy resin composition and preparation method thereof 深圳市安品有机硅材料有限公司 2022-03-25 — — CN disclosed
US-20120124896-A1 Diesel Composition and Method of Increasing Biodiesel Oxidation Stability RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC (CN) 2012-05-24 — — US disclosed
EP-2447344-A1 DIESEL COMPOSITION AND PROCESS FOR IMPROVING OXIDATION STABILITY OF BIODIESEL China Petroleum & Chemical Corporation (CN) 2012-05-02 — — EP disclosed
US-20120040916-A1 MOLECULAR INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-02-16 — — US disclosed
US-20120040916-A1 MOLECULAR INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-02-16 — — US disclosed
US-8007426-B2 Developing roller KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-08-30 — — US disclosed
US-8007426-B2 Developing roller KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-08-30 — — US disclosed
US-20110177338-A1 CARBON BLACK KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-07-21 — — US disclosed
US-20090116881-A1 INTERMEDIATE TRANSFER BELT KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-05-07 — — US disclosed
US-20090085013-A1 Composition Containing Carbon Black, Composition for Coloring and Conductive Composition KONICA MINOLTA BUSINESS TECHNOLOGIES, INC., (JP) 2009-04-02 — — US disclosed
US-20090085013-A1 Composition Containing Carbon Black, Composition for Coloring and Conductive Composition KONICA MINOLTA BUSINESS TECHNOLOGIES, INC., (JP) 2009-04-02 — — US disclosed
US-20090087766-A1 TONER FOR DEVELOPING ELECTROSTATIC LATENT IMAGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-04-02 — — US disclosed
US-20090087766-A1 TONER FOR DEVELOPING ELECTROSTATIC LATENT IMAGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-04-02 — — US disclosed
US-20090035027-A1 DEVELOPING ROLLER KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-02-05 — — US disclosed
US-20090035027-A1 DEVELOPING ROLLER KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-02-05 — — US disclosed
EP-1887048-A1 CARBON BLACK KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-02-13 — — EP disclosed
US-20070235692-A1 Nanophase carbon black grafted with organic compound in situ, synthesis thereof and articles therefrom EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2007-10-11 — — US disclosed
US-20070235692-A1 Nanophase carbon black grafted with organic compound in situ, synthesis thereof and articles therefrom EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2007-10-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120040916-A1 MOLECULAR INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY WNT1, CTNNB1, WNT3A MAPT 1720/4885HTT 3561/4885SMN1; SMN2 3897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.