Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | GAA | P10253 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603104 | 0.93 | GAA (0.47) | MAPTGAAKMT2AALDH1A1LMNA | |
| SCHEMBL11602024 | 0.92 | ALDH1A1 (0.56) | MAPTGAAKMT2AALDH1A1LMNA | |
| SCHEMBL11604385 | 0.83 | MAPT (0.47) | MAPTGAAKMT2AALDH1A1LMNA | |
| SCHEMBL11602011 | 0.79 | CTSD (0.47) | MAPTGAAKMT2AALDH1A1LMNA | |
| SCHEMBL11071184 | 0.78 | ALDH1A1 (0.58) | MAPTGAAKMT2AALDH1A1LMNA | |
| SCHEMBL11604261 | 0.78 | MAPT (0.47) | MAPTGAAKMT2AALDH1A1LMNA | |
| SCHEMBL11603753 | 0.78 | MAPT (0.50) | MAPTGAAKMT2AALDH1A1LMNA | |
| Bromide SCHEMBL31339526 | 0.77 | ALDH1A1 (0.56) | MAPTGAAKMT2AALDH1A1LMNA | |
| SCHEMBL11309247 | 0.76 | GAA (0.56) | MAPTGAAKMT2AALDH1A1LMNA | |
| SCHEMBL10900048 | 0.75 | KMT2A (0.49) | MAPTGAAKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096111-A | (BENZOTHIAZOLYL-THIO)-SUBSTITUTED ANTHRAQUINONES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |