Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 6/20 | 0.34 |
| ▸ | CA1 | P00915 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 6/20 | 0.34 |
| ▸ | CA7 | P43166 | 6/20 | 0.34 |
| ▸ | CA9 | Q16790 | 6/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31734107 | 0.87 | SERPINE1 (0.33) | — | |
| SCHEMBL31734106 | 0.84 | MAPK1 (0.38) | HIF1AMAPK1 | |
| SCHEMBL47924 | 0.77 | CA12 (0.42) | MAPTLMNASMN1; SMN2HSP90AA1HTT | |
| SCHEMBL11313304 | 0.72 | TSHR (0.36) | MAPTLMNASMN1; SMN2HSP90AA1HTT | |
| SCHEMBL28732750 | 0.71 | KDM4E (0.42) | MAPTLMNASMN1; SMN2HSP90AA1HTT | |
| Hydrochloric Acid SCHEMBL28484017 | 0.71 | TSHR (0.35) | MAPTLMNASMN1; SMN2HTTTSHR | |
| SCHEMBL13969442 | 0.69 | TSHR (0.42) | MAPTLMNASMN1; SMN2HSP90AA1HTT | |
| SCHEMBL4467924 | 0.68 | ALDH1A1 (0.41) | MAPTLMNASMN1; SMN2HSP90AA1HTT | |
| SCHEMBL5114658 | 0.68 | CA12 (0.43) | MAPTLMNASMN1; SMN2HSP90AA1HTT | |
| SCHEMBL15805131 | 0.68 | NFKB1 (0.39) | MAPTLMNAHTTTSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098816-A | HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-07-04 | — | — | US | disclosed |