Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.54 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.54 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | FADS1 | O60427 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 5/20 | 0.50 |
| ▸ | STK10 | O94804 | 3/20 | 0.50 |
| ▸ | SLK | Q9H2G2 | 3/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | TLK1 | Q9UKI8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27601546 | 0.95 | P2RY4 (0.57) | P2RY2P2RY4P2RY12DHODHFADS1 | |
| SCHEMBL11602772 | 0.83 | DHODH (0.49) | P2RY2P2RY4P2RY12DHODHMAPT | |
| SCHEMBL2612577 | 0.80 | MAPT (0.56) | P2RY2P2RY4P2RY12DHODHMAPT | |
| SCHEMBL30101406 | 0.80 | ADORA2A (0.55) | P2RY2P2RY4P2RY12MAPTMAPK1 | |
| SCHEMBL29963397 | 0.80 | ADORA2A (0.55) | P2RY2P2RY4P2RY12MAPTMAPK1 | |
| SCHEMBL11413805 | 0.80 | ADORA2A (0.55) | P2RY2P2RY4P2RY12MAPTMAPK1 | |
| SCHEMBL11790292 | 0.79 | FABP3 (0.48) | P2RY4DHODHMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL11791498 | 0.79 | CXCL8 (0.48) | P2RY4P2RY12DHODHMAPTMAPK1 | |
| SCHEMBL11538183 | 0.79 | MAPT (0.56) | P2RY4DHODHMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL625150 | 0.77 | MAPT (0.62) | P2RY2P2RY4P2RY12DHODHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4128396-A | Process for the improvement of dyeing properties of pigments of the anilino and arylmercapto anthraquinone series | CIBA-GEIGY CORPORATION (US) | 1978-12-05 | — | — | US | disclosed |
| US-3975410-A | Process for the manufacture of halogen-containing anthraquinoidal compounds, their use and new halogen-containing anthraquinoidal compounds | CIBA-GEIGY CORPORATION (US) | 1976-08-17 | — | — | US | disclosed |