Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 7/20 | 0.72 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.72 |
| ▸ | CCR1 | P32246 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11603080 | 0.99 | KCNA3 (0.70) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| Hydrochloric Acid SCHEMBL11605774 | 0.84 | KCNA3 (0.69) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| Diphenoxylate SCHEMBL42940 | 0.84 | OPRM1 (1.00) | KCNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL11604250 | 0.83 | KCNA3 (0.84) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| Diphenoxylate SCHEMBL28374697 | 0.83 | OPRM1 (0.98) | KCNA3OPRM1OPRD1OPRK1 | |
| Diphenoxylate SCHEMBL20595320 | 0.83 | OPRM1 (0.98) | KCNA3OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL11607175 | 0.83 | KCNA3 (0.80) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| Diphenoxylate SCHEMBL28385054 | 0.83 | OPRM1 (0.98) | KCNA3OPRM1OPRD1OPRK1 | |
| Diphenoxylate SCHEMBL42124 | 0.83 | OPRM1 (0.98) | KCNA3OPRM1OPRD1OPRK1 | |
| Diphenoxylate SCHEMBL28596518 | 0.83 | OPRM1 (0.98) | KCNA3OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076717-A | Derivatives of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid | G. D. SEARLE & CO. (US) | 1978-02-28 | — | — | US | claimed |