Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605874 | 0.81 | GAA (0.40) | CYP2C9KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9599595 | 0.74 | RAPGEF4 (0.38) | CYP2C9KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL11608011 | 0.70 | MAPT (0.51) | CYP2C9KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28160835 | 0.69 | KDM4E (0.54) | CYP2C9KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL28160834 | 0.68 | KDM4E (0.50) | CYP2C9KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL4636268 | 0.68 | ALDH1A1 (0.49) | CYP2C9KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL28161538 | 0.68 | KDM4E (0.46) | CYP2C9KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9599177 | 0.68 | RAPGEF4 (0.41) | CYP2C9KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL1288011 | 0.67 | SRC (0.55) | CYP2C9KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL20181600 | 0.67 | MIF (0.43) | CYP2C9ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4103012-A | CARDIOVASCULAR DISORDERS | LABAZ (FR) | 1978-07-25 | — | — | US | disclosed |