Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11775068 | 1.00 | SIRT2 (0.42) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL11779345 | 1.00 | SIRT2 (0.42) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL11773588 | 1.00 | SIRT2 (0.42) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL8413376 | 1.00 | SIRT2 (0.42) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL2233403 | 0.98 | SIRT2 (0.40) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL28179569 | 0.91 | GAA (0.36) | SIRT2GAAALDH1A1 | |
| SCHEMBL3490658 | 0.89 | GAA (0.43) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| Decane SCHEMBL3423075 | 0.89 | LMNA (0.42) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| Tridecane SCHEMBL4180613 | 0.89 | LMNA (0.42) | SIRT2GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL11351135 | 0.89 | GAA (0.37) | SIRT2GAALMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4090019-A | Geminal prostaglandin analogs | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1978-05-16 | — | — | US | disclosed |
| US-4089897-A | Geminal prostaglandin analogs | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1978-05-16 | — | — | US | disclosed |