Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4359771 | 0.98 | GAA (0.40) | GAASIRT2LMNAALDH1A1HSD17B10 | |
| SCHEMBL11775068 | 0.89 | SIRT2 (0.42) | GAASIRT2LMNAALDH1A1HSD17B10 | |
| SCHEMBL11779345 | 0.89 | SIRT2 (0.42) | GAASIRT2LMNAALDH1A1HSD17B10 | |
| SCHEMBL11607014 | 0.89 | SIRT2 (0.42) | GAASIRT2LMNAALDH1A1HSD17B10 | |
| SCHEMBL8413376 | 0.89 | SIRT2 (0.42) | GAASIRT2LMNAALDH1A1HSD17B10 | |
| SCHEMBL11773588 | 0.89 | SIRT2 (0.42) | GAASIRT2LMNAALDH1A1HSD17B10 | |
| SCHEMBL773239 | 0.87 | OPRM1 (0.40) | MEN1KMT2A | |
| SCHEMBL2233403 | 0.86 | SIRT2 (0.40) | GAASIRT2LMNAALDH1A1HSD17B10 | |
| SCHEMBL798410 | 0.86 | OPRM1 (0.38) | GAASIRT2 | |
| SCHEMBL28008290 | 0.85 | TSHR (0.47) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754675-B2 | 2-heptylcyclopropyl-1-carboxylic acid | SYMRISE GMBH & CO. KG (DE) | 2010-07-13 | — | — | US | disclosed |
| US-20060128603-A1 | 2-heptylcyclopropyl-1-carboxylic acid | SYMRISE GMBH & CO. KG (DE) | 2006-06-15 | — | — | US | disclosed |
| EP-1565423-B1 | 2-HEPTYLCYCLOPROPYL-1-CARBOXYLIC ACID | SYMRISE GMBH & CO KG (DE) | 2006-06-07 | — | — | EP | disclosed |
| EP-1565423-A1 | 2-HEPTYLCYCLOPROPYL-1-CARBOXYLIC ACID | Symrise GmbH & Co. KG (DE) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004046079-A1 | 2-HEPTYLCYCLOPROPYL-1-CARBOXYLIC ACID | SYMRISE GMBH & CO. KG (DE) | 2004-06-03 | — | — | WO | disclosed |