Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19707986 | 0.98 | MGLL (0.64) | MGLLKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11610461 | 0.94 | MGLL (0.60) | MGLLKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11607013 | 0.92 | MGLL (0.58) | MGLLKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11607842 | 0.90 | MGLL (0.56) | MGLLKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11611789 | 0.86 | MGLL (0.51) | MGLLKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3856849 | 0.86 | MGLL (0.51) | MGLLKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11610767 | 0.82 | CASP6 (0.50) | MGLLKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11649332 | 0.81 | MGLL (0.64) | MGLLKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11612454 | 0.81 | POLB (0.51) | MGLLKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11607688 | 0.81 | SCN2A (0.53) | MGLLKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099007-A | N,N-SUBSTITUTED 2,4,5-TRIKETOIMIDAZOLIDINES AND A PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-07-04 | — | — | US | disclosed |