Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448179 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL9349244 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL31647123 | 0.82 | ALDH1A1 (0.57) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL11133077 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MEN1POLBKMT2ATSHR | |
| SCHEMBL9516555 | 0.80 | POLB (0.59) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL11130878 | 0.78 | KYNU (0.37) | ALDH1A1MEN1KMT2APKMMAPT | |
| SCHEMBL913390 | 0.77 | ALDH1A1 (0.68) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL1564742 | 0.77 | KMT2A (0.67) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL30932792 | 0.77 | KMT2A (0.67) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL11102994 | 0.76 | MEN1 (0.54) | ALDH1A1MEN1POLBKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076825-A | Method of treating helminthiasis by parenteral or topical administration of sulfoxide derivatives of benzimidazoles | E. R. SQUIBB & SONS, INC. (US) | 1978-02-28 | — | — | US | disclosed |