Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11608639 | 1.00 | ALDH1A1 (0.32) | ALDH1A1ALDH2MEN1POLBMAPT | |
| SCHEMBL11607298 | 0.82 | MAPT (0.34) | ALDH1A1MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL11607801 | 0.82 | KMT2A (0.33) | ALDH1A1ALDH2MEN1MAPTKMT2A | |
| SCHEMBL11607296 | 0.82 | MAPT (0.34) | ALDH1A1MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL11609102 | 0.77 | CA12 (0.40) | ALDH1A1MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL11609098 | 0.77 | CA12 (0.40) | ALDH1A1MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL11604584 | 0.73 | ALDH1A1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL11604586 | 0.73 | ALDH1A1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL11610275 | 0.72 | MAPT (0.35) | ALDH1A1ALDH2MEN1MAPTKMT2A | |
| SCHEMBL11610271 | 0.72 | MAPT (0.35) | ALDH1A1ALDH2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075001-A | 3-Aminoisothiazole derivatives as herbicides | FMC CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |