Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11607866 | 0.86 | MGLL (0.56) | NPC1RAB9AKMT2ACASP3SENP8 | |
| SCHEMBL11610513 | 0.84 | KMT2A (0.48) | NPC1RAB9AKMT2ATDP1THRA | |
| SCHEMBL11611777 | 0.82 | KMT2A (0.53) | NPC1RAB9AKMT2ACASP3SENP8 | |
| SCHEMBL2796515 | 0.77 | TAAR1 (0.52) | ABCC1MLYCDMGLLNPY5R | |
| SCHEMBL11608219 | 0.76 | NPC1 (0.73) | NPC1RAB9AKMT2ACASP3SENP8 | |
| SCHEMBL11607872 | 0.73 | IDO1 (0.57) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL11609156 | 0.72 | KMT2A (0.45) | KMT2ATDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL11606189 | 0.72 | MGLL (0.59) | NPC1RAB9AKMT2AABCC1SMN1; SMN2 | |
| SCHEMBL11610548 | 0.72 | KMT2A (0.52) | NPC1RAB9AKMT2AABCC1SMN1; SMN2 | |
| SCHEMBL12133560 | 0.72 | MLYCD (0.72) | KMT2AHDAC1HDAC6MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076814-A | DITHIOCARBAMIC ACID DERIVATIVES | SANKYO COMPANY LIMITED (JA) | 1978-02-28 | — | — | US | disclosed |