Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603940 | 1.00 | HCAR2 (0.55) | HCAR2TDP1SERPINE1LMNAAKR1B10 | |
| SCHEMBL9421257 | 0.86 | TDP1 (0.62) | TDP1SERPINE1LMNAKMT2ASLC7A5 | |
| SCHEMBL27574211 | 0.84 | TDP1 (0.60) | TDP1SERPINE1LMNAKMT2ASLC7A5 | |
| SCHEMBL8982607 | 0.84 | THRB (0.53) | TDP1SERPINE1LMNAKMT2ASLC7A5 | |
| SCHEMBL29997084 | 0.84 | THRB (0.53) | TDP1SERPINE1LMNAKMT2ASLC7A5 | |
| SCHEMBL8944708 | 0.82 | SERPINE1 (0.43) | HCAR2TDP1SERPINE1LMNAKMT2A | |
| SCHEMBL11007649 | 0.82 | SERPINE1 (0.43) | HCAR2TDP1SERPINE1LMNAKMT2A | |
| SCHEMBL2204656 | 0.81 | TDP1 (0.61) | TDP1SERPINE1LMNAKMT2A | |
| SCHEMBL209607 | 0.81 | TDP1 (0.71) | TDP1LMNAKMT2A | |
| Isophthalic Acid SCHEMBL28926291 | 0.80 | KMT2A (0.58) | HCAR2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067845-A | OXIDES OR HYDROXIDES OF MAGNESIUM OR CALCIUM, AND A POLYISOCYANATE | THE BUDD COMPANY (US) | 1978-01-10 | — | — | US | disclosed |