Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11007649 | 1.00 | SERPINE1 (0.43) | SERPINE1HCAR2MAPK1HIF1AKMT2A | |
| SCHEMBL10348750 | 0.84 | MAPK1 (0.51) | SERPINE1MAPK1HIF1AKMT2AALDH1A1 | |
| SCHEMBL11603940 | 0.82 | HCAR2 (0.55) | SERPINE1HCAR2KMT2ATDP1LMNA | |
| SCHEMBL11608897 | 0.82 | HCAR2 (0.55) | SERPINE1HCAR2KMT2ATDP1LMNA | |
| SCHEMBL3298195 | 0.81 | MAPK1 (0.47) | SERPINE1MAPK1HIF1AKMT2AALDH1A1 | |
| SCHEMBL8944715 | 0.79 | ALDH1A1 (0.47) | HCAR2KMT2AALDH1A1TDP1MEN1 | |
| SCHEMBL9988314 | 0.79 | MAPK1 (0.51) | SERPINE1MAPK1HIF1AKMT2AALDH1A1 | |
| Terephthalic Acid SCHEMBL6690763 | 0.79 | MAPK1 (0.45) | SERPINE1MAPK1HIF1AKMT2AALDH1A1 | |
| Ethylene Glycol SCHEMBL8373776 | 0.79 | MAPK1 (0.45) | SERPINE1MAPK1HIF1AKMT2AALDH1A1 | |
| Isophthalic Acid SCHEMBL8944713 | 0.76 | RXRA (0.44) | KMT2AALDH1A1MAPTNR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545679-A | CURRENT LIMITERS, RESETTABLE FUSES | EATON CORPORATION (US) | 1996-08-13 | — | — | US | claimed |
| US-5545679-A | CURRENT LIMITERS, RESETTABLE FUSES | EATON CORPORATION (US) | 1996-08-13 | — | — | US | disclosed |
| US-5545679-A | CURRENT LIMITERS, RESETTABLE FUSES | EATON CORPORATION (US) | 1996-08-13 | — | — | US | disclosed |