Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600798 | 0.79 | CYP1A2 (0.47) | ALDH1A1POLBLMNAHSD17B10GAA | |
| SCHEMBL10704882 | 0.75 | FAAH (0.69) | FAAHALDH1A1GLO1LMNAHSD17B10 | |
| SCHEMBL135497 | 0.75 | LMNA (0.44) | ALDH1A1POLBLMNAHSD17B10MAPT | |
| SCHEMBL1705915 | 0.74 | LMNA (0.44) | ALDH1A1LMNAHSD17B10MEN1ALOX15 | |
| SCHEMBL11438320 | 0.74 | GAA (0.41) | ALDH1A1POLBLMNAGAARAB9A | |
| SCHEMBL1707150 | 0.73 | TSHR (0.48) | ALDH1A1LMNAHPGDKMT2ATSHR | |
| SCHEMBL10711315 | 0.73 | TDP1 (0.41) | ALDH1A1POLBLMNAHSD17B10MAPT | |
| SCHEMBL18101453 | 0.73 | FAAH (0.60) | FAAHALDH1A1GLO1LMNAHSD17B10 | |
| SCHEMBL5124190 | 0.73 | TSHR (0.46) | ALDH1A1LMNAHSD17B10MEN1ALOX15 | |
| SCHEMBL5130352 | 0.72 | TSHR (0.47) | ALDH1A1LMNAHPGDL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067885-A | Intermediate in the preparation of 6,6-alkylenedioxyalkan-2-ones | HOFFMANN-LA ROCHE INC. (US) | 1978-01-10 | — | — | US | disclosed |
| US-3972898-A | Process for the preparation of 6,6-alkylenedioxyalkan-2-ones | HOFFMANN-LA ROCHE INC. (US) | 1976-08-03 | — | — | US | disclosed |