Methylamine

Methylamine

SCHEMBL11609028

CN.O=[N+]([O-])c1c[nH]nc1-c1ccco1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
POLB P06746 3/20 0.41
MAPT P10636 3/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
PKM P14618 2/20 0.41
HPGD P15428 2/20 0.41
ALOX15 P16050 2/20 0.41
CASP1 P29466 2/20 0.41
PTPN7 P35236 2/20 0.41
RECQL P46063 2/20 0.41
BLM P54132 2/20 0.41
CASP7 P55210 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11605248 0.95 MEN1 (0.44) MEN1KMT2APOLBMAPTKDM4E
SCHEMBL11624096 0.73 KDM4E (0.50) MEN1KMT2APOLBMAPTKDM4E
SCHEMBL30502861 0.71 KMT2A (0.47) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL6322672 0.71 MAPT (0.44) MEN1KMT2APOLBMAPTKDM4E
SCHEMBL11606639 0.71 HSP90AA1 (0.52) MEN1KMT2APOLBMAPTKDM4E
SCHEMBL5242265 0.69 KMT2A (0.49) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL11608146 0.69 ALDH1A1 (0.46) MEN1KMT2APOLBMAPTKDM4E
SCHEMBL4054189 0.68 PIK3R1 (0.47) MEN1KMT2APOLBMAPTKDM4E
SCHEMBL27973799 0.67 ERN1 (0.43) MEN1KMT2APOLBMAPTKDM4E
SCHEMBL6209560 0.67 POLB (0.43) MEN1KMT2APOLBMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4093812-A MICROBIOCIDES, DISINFECTANTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1978-06-06 US disclosed