Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | BLM | P54132 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890302 | 0.75 | — | — | |
| SCHEMBL1260158 | 0.73 | MAPT (0.45) | MAPTTDP1MEN1ALDH1A1HPGD | |
| SCHEMBL11605248 | 0.70 | MEN1 (0.44) | POLBMAPTTDP1BLMKDM4E | |
| SCHEMBL11606639 | 0.70 | HSP90AA1 (0.52) | POLBMAPTTDP1BLMKDM4E | |
| SCHEMBL7749946 | 0.69 | HSD17B10 (0.41) | MAPTTDP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL7749941 | 0.68 | ACHE (0.41) | POLBMAPTMEN1ALDH1A1HPGD | |
| Methylamine SCHEMBL11609028 | 0.67 | MEN1 (0.41) | POLBMAPTTDP1BLMKDM4E | |
| SCHEMBL6322672 | 0.67 | MAPT (0.44) | POLBMAPTTDP1BLMKDM4E | |
| Hydrochloric Acid SCHEMBL6371847 | 0.65 | CHEK1 (0.54) | MAPTHPGDALOX15LMNACHEK1 | |
| SCHEMBL1496181 | 0.64 | CSNK2A2 (0.49) | POLBMAPTMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124827-B1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2005-11-30 | — | — | EP | disclosed |
| EP-1123281-B1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED CYCLOPROPYL)-1,2,4-TRIAZOLE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1123287-B1 | INSECTICIDAL 3- (SUBSTITUTED PYRIDYL) -1, 2, 4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6417187-B2 | PALLADIUM CATALYZED ARYLATION, ALKYLATION, DEIODINATION OR DEBROMINATION | DOW AGROSCIENCES LLC | 2002-07-09 | — | — | US | disclosed |
| US-6413997-B1 | INSECTICIDES, MITICIDES | DOW AGROSCIENCES LLC | 2002-07-02 | — | — | US | disclosed |
| US-6413992-B1 | 3-(substituted pyridyl)-1,2,4-triazole compounds | DOW AGROSCIENCES LLC | 2002-07-02 | — | — | US | disclosed |
| US-20020019370-A1 | Palladium catalyzed arylation, alkylation, deiodination or debromination | DOW AGROSCIENCES LLC | 2002-02-14 | — | — | US | disclosed |
| EP-0922043-B1 | PESTICIDAL 3-(SUBSTITUTED PHENYL)-5-(THIENYL OR FURYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2002-01-30 | — | — | EP | disclosed |
| EP-1124827-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | Dow AgroSciences LLC (US) | 2001-08-22 | — | — | EP | disclosed |
| EP-1123281-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED CYCLOPROPYL)-1,2,4-TRIAZOLE COMPOUNDS | Dow AgroSciences LLC (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-1123287-A1 | INSECTICIDAL 3- (SUBSTITUTED PYRIDYL) -1, 2, 4-TRIAZOLES | Dow AgroSciences LLC (US) | 2001-08-16 | — | — | EP | disclosed |
| US-6262305-B1 | Process and intermediates for preparing 3-(substituted phenyl)-5-(thienyl or furyl)-1,2,4-triazole compounds | DOW AGROSCIENCES LLC | 2001-07-17 | — | — | US | disclosed |
| US-6262099-B1 | USEFUL AS INSECTICIDES AND ACARICIDES. | DOW AGROSCIENCES LLC | 2001-07-17 | — | — | US | disclosed |
| WO-2000024739-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |
| WO-2000024720-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED CYCLOPROPYL)-1,2,4-TRIAZOLE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |
| WO-2000024735-A1 | INSECTICIDAL 1-(SUBSTITUTED PYRIDYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |
| US-6015826-A | INSECTICIDES, APHIDICIDES, AND MITICIDES | DOW AGROSCIENCES LLC | 2000-01-18 | — | — | US | disclosed |
| EP-0922043-A1 | PESTICIDAL 3-(SUBSTITUTED PHENYL)-5-(THIENYL OR FURYL)-1,2,4-TRIAZOLES | Dow AgroSciences LLC (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998047894-A1 | PESTICIDAL 3-(SUBSTITUTED PHENYL)-5-(THIENYL OR FURYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 1998-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019370-A1 | Palladium catalyzed arylation, alkylation, deiodination or debromination | DDT, TYR, DDC | POLB 2971/4885MAPT 4029/4885TDP1 937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.