Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | MGMT | P16455 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647298 | 0.82 | MAOA (0.42) | MAOAMAOBNPSR1CDK1CCNB1 | |
| SCHEMBL1770767 | 0.79 | MAOA (0.40) | MAOAMAOBNPSR1RAB9AALDH1A1 | |
| SCHEMBL1617208 | 0.71 | STAT3 (0.52) | RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL3752087 | 0.71 | MAOA (0.50) | MAOAMAOBCDK1CCNB1MGMT | |
| SCHEMBL9843340 | 0.69 | MAOA (0.38) | MAOAMAOBCDK1CCNB1MGMT | |
| SCHEMBL9330920 | 0.69 | MAOA (0.48) | MAOAMAOBCDK1CCNB1MGMT | |
| SCHEMBL809311 | 0.68 | MAOA (0.52) | MAOAMAOBNPSR1KMT2AALDH1A1 | |
| SCHEMBL28526172 | 0.67 | MAOA (0.47) | MAOAMAOBNPSR1KMT2AALDH1A1 | |
| SCHEMBL58239 | 0.67 | MAOA (0.47) | MAOAMAOBALDH1A1MAPT | |
| SCHEMBL5143592 | 0.67 | TDP1 (0.57) | RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080497-A | PESTICIDES | THE DOW CHEMICAL COMPANY (US) | 1978-03-21 | — | — | US | disclosed |
| US-3954746-A | BACTERICIDES, FUNGICIDES | THE DOW CHEMICAL COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
| US-3954747-A | BACTERICIDES, FUNGICIDES | THE DOW CHEMICAL COMPANY (US) | 1976-05-04 | — | — | US | disclosed |