Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | MGMT | P16455 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843337 | 0.73 | TSHR (0.36) | MAOAMAOBTSHRCYP1A2CYP3A4 | |
| SCHEMBL3752087 | 0.71 | MAOA (0.50) | MAOAMAOBCYP3A4SMN1; SMN2LMNA | |
| SCHEMBL7900085 | 0.69 | POLB (0.44) | MAOAMAOBTSHRSMN1; SMN2LMNA | |
| SCHEMBL11609342 | 0.69 | MAOA (0.38) | MAOAMAOBCA2MAPTKMT2A | |
| SCHEMBL9330920 | 0.69 | MAOA (0.48) | MAOAMAOBTSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL809311 | 0.68 | MAOA (0.52) | MAOAMAOBTSHRCYP3A4CA2 | |
| SCHEMBL58239 | 0.67 | MAOA (0.47) | MAOAMAOBTSHRMAPTCYP2C19 | |
| SCHEMBL27591269 | 0.67 | MAOA (0.42) | MAOAMAOBCDK1CCNB1MGMT | |
| SCHEMBL5143592 | 0.67 | TDP1 (0.57) | TSHRCYP1A2CYP2C9SMN1; SMN2LMNA | |
| SCHEMBL9551202 | 0.67 | MAOA (0.42) | MAOAMAOBTSHRMAPTCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435794-A1 | Alkenyl- or heteroaryl thio, sulfone, sulfoxy herbicides | RHONE-POULENC AGROCHIMIE (FR) | 1991-07-03 | — | — | EP | disclosed |