Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11606987 | 0.77 | MAPT (0.44) | KMT2ALMNAPOLBMEN1SMN1; SMN2 | |
| SCHEMBL11613758 | 0.76 | PPARA (0.49) | KMT2ACYP1A2CYP2C9CYP2C19ADORA3 | |
| SCHEMBL117259 | 0.68 | CYP1A2 (0.65) | CYP1A2CYP2C9CYP2C19EPHX2POLB | |
| SCHEMBL2399722 | 0.68 | CYP1A2 (0.65) | CYP1A2CYP2C9CYP2C19EPHX2POLB | |
| SCHEMBL607372 | 0.68 | CYP1A2 (0.65) | CYP1A2CYP2C9CYP2C19EPHX2POLB | |
| SCHEMBL10607544 | 0.68 | CYP1A2 (0.57) | KMT2ACYP1A2CYP2C9CYP2C19EPHX2 | |
| SCHEMBL8761273 | 0.68 | CYP1A2 (0.57) | KMT2ACYP1A2CYP2C9CYP2C19EPHX2 | |
| SCHEMBL10812072 | 0.68 | ACE (0.49) | KMT2ACYP1A2CYP2C9CYP2C19LMNA | |
| Hydrochloric Acid SCHEMBL11632943 | 0.67 | CYP1A2 (0.62) | CYP1A2CYP2C9CYP2C19EPHX2POLB | |
| SCHEMBL20591019 | 0.67 | CYP1A2 (0.62) | CYP1A2CYP2C9CYP2C19EPHX2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073918-A | HYPOCHOLESTEREMIC AGENTS | LUDWIG MERCKLE KG (DT) | 1978-02-14 | — | — | US | claimed |
| US-4073918-A | HYPOCHOLESTEREMIC AGENTS | LUDWIG MERCKLE KG (DT) | 1978-02-14 | — | — | US | disclosed |