SCHEMBL11609583

SCHEMBL11609583

CC(C)(C)OC(=O)c1c(S)c(C(C)(C)C)c(O)c(C(C)(C)C)c1S

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GRM6 O15303 1/20 0.31
IGF1R P08069 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11605390 0.83 CA1 (0.39) NPSR1
SCHEMBL11608593 0.78 CYP2C19 (0.39) CYP2C19NPSR1GRM6
SCHEMBL9015593 0.76 CYP2C9 (0.33) CYP2C9CYP2C19NPSR1GRM6
SCHEMBL9108516 0.76 GLRA3 (0.45)
SCHEMBL11613178 0.76 ESR1 (0.41)
SCHEMBL27274620 0.73 GRM6 (0.37) CYP2C9CYP2C19NPSR1GRM6IGF1R
SCHEMBL11607397 0.73
SCHEMBL2221008 0.71 GRM6 (0.36) CYP2C9CYP2C19NPSR1GRM6IGF1R
SCHEMBL11605716 0.71 LMNA (0.48)
SCHEMBL11608118 0.71 KMT2A (0.41) CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4083989-A MORPHOGENETIC HORMONAL MIMETIC ACTIVITY CHEVRON RESEARCH COMPANY (US) 1978-04-11 US disclosed
US-3988471-A Insect control employing certain benzoates CHEVRON RESEARCH COMPANY (US) 1976-10-26 US disclosed