SCHEMBL9015593

SCHEMBL9015593

CC(C)(C)OC(=O)c1c2c(C(C)(C)C)c(O)c(C(C)(C)C)c1OO2

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GRM6 O15303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9015742 0.83
SCHEMBL9015736 0.77 GLRA3 (0.44)
SCHEMBL11609583 0.76 CYP2C9 (0.33) CYP2C9CYP2C19NPSR1GRM6
SCHEMBL27274620 0.72 GRM6 (0.37) CYP2C9CYP2C19NPSR1GRM6
SCHEMBL2221008 0.70 GRM6 (0.36) CYP2C9CYP2C19NPSR1MAPTGRM6
SCHEMBL31514519 0.69 ALDH1A1 (0.41) CYP2C9CYP2C19NPSR1TP53MAPT
SCHEMBL17982745 0.68 EGFR (0.36) CYP2C9CYP2C19NPSR1MAPTGRM6
SCHEMBL27987654 0.67 GRM6 (0.45) NPSR1MAPTHSD17B10GRM6
SCHEMBL18047574 0.66 FFAR1 (0.45) CYP2C9CYP2C19NPSR1GRM6
SCHEMBL10470928 0.65 NPSR1 (0.37) CYP2C9CYP2C19NPSR1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5516856-A IMPROVED PROCESS FOR THE MODIFICATION OF THE MOLECULAR CHAIN OF A POLYMER ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-05-14 US disclosed
US-5051531-A As polymerization catalysts and for crosslinking ATOCHEM NORTH AMERICA, INC. (US) 1991-09-24 US disclosed