Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11608790 | 0.89 | ADRB2 (0.48) | ADRB2DNM1HTR1ASLC6A2ADRA2A | |
| Acetic Acid SCHEMBL11609882 | 0.86 | ADRB2 (0.60) | ADRB2DNM1HTR1ADRD3SLC6A2 | |
| SCHEMBL11610687 | 0.86 | ADRB2 (0.64) | ADRB2DNM1HTR1ADRD3SLC6A2 | |
| SCHEMBL10806729 | 0.82 | ADRB2 (0.69) | ADRB2DNM1HTR1ADRD3SLC6A2 | |
| SCHEMBL9856129 | 0.82 | ADRB2 (0.69) | ADRB2DNM1HTR1ADRD3SLC6A2 | |
| SCHEMBL9856507 | 0.82 | ADRB2 (0.69) | ADRB2DNM1HTR1ADRD3SLC6A2 | |
| SCHEMBL11617082 | 0.78 | ADRB2 (0.53) | ADRB2DNM1HTR1ADRD3SLC6A2 | |
| SCHEMBL11610173 | 0.76 | ADRB2 (0.59) | ADRB2DNM1HTR1AADRA2AADRB3 | |
| SCHEMBL11613757 | 0.73 | ADRB2 (0.48) | ADRB2DNM1HTR1ADRD3SLC6A2 | |
| Acetic Acid SCHEMBL11616920 | 0.72 | ADRB2 (0.44) | ADRB2DNM1SLC6A2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4120963-A | BLOOD DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1978-10-17 | — | — | US | disclosed |