Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11735415 | 0.83 | ADRB2 (0.48) | ALDH1A1ADRB2ADRB1ADRB3RECQL | |
| SCHEMBL11608097 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1RECQLTSHRUSP2 | |
| SCHEMBL25221249 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1ADRB2 | |
| SCHEMBL25625452 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1CYP1A2 | |
| SCHEMBL18834525 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1TSHR | |
| SCHEMBL11712159 | 0.75 | EPHX1 (0.50) | ALDH1A1RECQLTSHRCCNE1CDK2 | |
| SCHEMBL16028881 | 0.74 | CYP4F2 (0.45) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1CYP4Z1 | |
| SCHEMBL19628552 | 0.74 | FDPS (0.44) | CCNE1CDK2CDK5 | |
| SCHEMBL1567646 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1CYP1A2 | |
| SCHEMBL20033831 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073919-A | Hypolipemiant compositions and methods | ROUSSEL UCLAF (FR) | 1978-02-14 | — | — | US | disclosed |
| US-4032643-A | ANTILIPOLYTIC AGENTS, VASODILATION, ANTIBRADYKINETIC AGENTS | ROUSSEL-UCLAF (FR) | 1977-06-28 | — | — | US | disclosed |