Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054659 | 0.86 | PTPRC (0.45) | ADORA1ADORA3ADORA2APTPRCALDH1A1 | |
| SCHEMBL11608972 | 0.80 | MAOA (0.49) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL29111497 | 0.79 | PTGDR2 (0.49) | PTGDR2ADORA1ADORA3ADORA2AALDH1A1 | |
| SCHEMBL3789504 | 0.79 | PTGDR2 (0.65) | PTGDR2ADORA1ADORA3ADORA2APTPRC | |
| SCHEMBL18725073 | 0.79 | PTPRC (0.55) | PTPRCALDH1A1RAB9ANPSR1ADRB2 | |
| SCHEMBL12629268 | 0.78 | SYK (0.56) | PTGDR2ADORA3MAPTKDM4EHSD17B10 | |
| SCHEMBL203121 | 0.77 | ADRB2 (0.61) | ADORA1ADORA3ADORA2APTPRCALDH1A1 | |
| Propane SCHEMBL27542299 | 0.76 | ADRB2 (0.59) | ADORA1ADORA3ADORA2APTPRCALDH1A1 | |
| Fluoride SCHEMBL27432507 | 0.76 | ADRB2 (0.59) | ADORA1ADORA3ADORA2APTPRCALDH1A1 | |
| SCHEMBL9474035 | 0.76 | TSHR (0.60) | PTGDR2ALDH1A1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4105668-A | 6-AMINO-2,2-DIMETHYL-3-(1 -SUBSTITUTED TETRAZOL-5-YL)PENAM COMPOUND REACTED WITH HYDROGEN FLUORIDE | PFIZER INC. (US) | 1978-08-08 | — | — | US | disclosed |