Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11616304 | 0.87 | HTR2A (0.46) | HTR2AHTR2BHTR2CTAAR1MAOB | |
| SCHEMBL11614808 | 0.81 | PNMT (0.46) | TAAR1IDO1PNMT | |
| SCHEMBL11519063 | 0.79 | HTR2A (0.48) | HTR2AHTR2BHTR2CTAAR1MAOB | |
| SCHEMBL11613544 | 0.79 | TRPA1 (0.56) | TAAR1SIGMAR1LMNASLC6A4 | |
| SCHEMBL11614193 | 0.77 | HTR2A (0.49) | HTR2AHTR2BHTR2CTAAR1MAOB | |
| SCHEMBL11615312 | 0.74 | TAAR1 (0.51) | HTR2AHTR2BHTR2CTAAR1IDO1 | |
| SCHEMBL1720376 | 0.74 | HTR2A (0.54) | HTR2AHTR2BHTR2CTAAR1MAOB | |
| SCHEMBL1720582 | 0.74 | HTR2A (0.59) | HTR2AHTR2BHTR2CTAAR1MAOB | |
| SCHEMBL19040917 | 0.74 | HTR2A (0.54) | HTR2AHTR2BHTR2CTAAR1MAOB | |
| SCHEMBL73993 | 0.73 | HTR2A (0.58) | HTR2AHTR2BHTR2CTAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122282-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-10-24 | — | — | US | disclosed |
| US-4107191-A | PROSTAGLANDINS, BLOOD PRESSURE LOWERING, LABOR INDUCTION, REPRODUCTIVE-CYCLE REGULATION, GASTRIC ANTISECRETORY | THE UPJOHN COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-4104474-A | PROSTAGLANDINS, HYPOTENSIVE, OXYTOCICS, ANTIFERTILITY, ANTISECRETORY | THE UPJOHN COMPANY (US) | 1978-08-01 | — | — | US | disclosed |
| US-4099015-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4086258-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-04-25 | — | — | US | disclosed |
| US-4085139-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4081478-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-4073808-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-4058564-A | PROSTAGLANDINS; HYPOTENSIVE, LABOR INDUCERS, ANTISECRETORY | THE UPJOHN COMPANY (US) | 1977-11-15 | — | — | US | disclosed |
| US-4029681-A | 13,14-Didehydro-PG analogs | THE UPJOHN COMPANY (US) | 1977-06-14 | — | — | US | disclosed |
| US-4018803-A | 13,14-Didehydro-PG3 compounds | THE UPJOHN COMPANY (US) | 1977-04-19 | — | — | US | disclosed |