Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.45 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.44 |
| ▸ | GAPDH | P04406 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746975 | 0.87 | ALDH1A1 (0.46) | PTGFRALDH1A1PTGER4SLCO2A1TBXA2R | |
| SCHEMBL11508604 | 0.86 | ALDH1A1 (0.52) | PTGFRALDH1A1PTGER4SLCO2A1TBXA2R | |
| SCHEMBL11508605 | 0.86 | ALDH1A1 (0.52) | PTGFRALDH1A1PTGER4SLCO2A1TBXA2R | |
| SCHEMBL11508606 | 0.86 | ALDH1A1 (0.52) | PTGFRALDH1A1PTGER4SLCO2A1TBXA2R | |
| SCHEMBL11531089 | 0.84 | PDE4D (0.36) | PTGFRALDH1A1PTGER4SLCO2A1TBXA2R | |
| SCHEMBL11720178 | 0.82 | TBXA2R (0.62) | PTGFRALDH1A1PTGER4SLCO2A1TBXA2R | |
| SCHEMBL11538480 | 0.82 | ALDH1A1 (0.57) | PTGFRALDH1A1PTGER4SLCO2A1TBXA2R | |
| SCHEMBL13468495 | 0.81 | ALDH1A1 (0.70) | PTGFRALDH1A1PTGER4SLCO2A1TBXA2R | |
| SCHEMBL11727043 | 0.81 | ALDH1A1 (0.61) | PTGFRALDH1A1PTGER4SLCO2A1TBXA2R | |
| SCHEMBL13468478 | 0.81 | PTGFR (0.59) | PTGFRALDH1A1PTGER4SLCO2A1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122282-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-10-24 | — | — | US | disclosed |
| US-4085139-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4081478-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-4073808-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-4013695-A | PROSTAGLANDINS, HYPOTENSIVES, OXYTOCICS, ANTISECRETORY AND ANTIULCER AGENTS, REPRODUCTION CONTROL | THE UPJOHN COMPANY (US) | 1977-03-22 | — | — | US | disclosed |