Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612842 | 0.88 | KMT2A (0.52) | RAB9AKMT2AMAPTALOX15ALDH1A1 | |
| SCHEMBL11615774 | 0.86 | KMT2A (0.53) | RAB9AKMT2AMAPTALOX15KDM4E | |
| SCHEMBL11613986 | 0.85 | KMT2A (0.53) | RAB9AKMT2AMAPTALOX15KDM4E | |
| SCHEMBL11615128 | 0.84 | KMT2A (0.47) | RAB9AKMT2AMAPTALOX15KDM4E | |
| SCHEMBL11615175 | 0.84 | MAPT (0.52) | RAB9AKMT2AMAPTALOX15KDM4E | |
| SCHEMBL11613653 | 0.84 | MAPT (0.52) | RAB9AKMT2AMAPTALOX15MEN1 | |
| SCHEMBL11615378 | 0.83 | KMT2A (0.49) | RAB9AKMT2AMAPTALOX15KDM4E | |
| SCHEMBL11619227 | 0.83 | MAPT (0.53) | KMT2AMAPTALOX15MAPK1KDM4E | |
| SCHEMBL11610558 | 0.82 | MAPT (0.50) | RAB9AKMT2AMAPTALOX15KDM4E | |
| SCHEMBL11618012 | 0.82 | KMT2A (0.42) | RAB9AKMT2AMAPTALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |