Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612842 | 0.87 | KMT2A (0.52) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL11612294 | 0.83 | RAB9A (0.48) | MAPTKDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL11610558 | 0.79 | MAPT (0.50) | MAPTKDM4EALDH1A1LMNATP53 | |
| SCHEMBL11615203 | 0.77 | HPGD (0.53) | MAPTALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL11613653 | 0.75 | MAPT (0.52) | MAPTTP53KMT2AMEN1ALOX15 | |
| SCHEMBL11618012 | 0.74 | KMT2A (0.42) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL11615915 | 0.74 | KMT2A (0.52) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL11615128 | 0.72 | KMT2A (0.47) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11613055 | 0.72 | MAPT (0.43) | MAPTKDM4EALDH1A1HTTLMNA | |
| SCHEMBL11611989 | 0.71 | KMT2A (0.50) | MAPTALDH1A1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |