Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612294 | 0.88 | RAB9A (0.48) | KMT2AGAAALDH1A1MEN1MAPT | |
| SCHEMBL11619227 | 0.87 | MAPT (0.53) | KMT2AALDH1A1MEN1MAPTALOX15 | |
| SCHEMBL11615915 | 0.86 | KMT2A (0.52) | KMT2AGAAALDH1A1MEN1MAPT | |
| SCHEMBL11611989 | 0.83 | KMT2A (0.50) | KMT2AGAAALDH1A1MEN1MAPT | |
| SCHEMBL11615509 | 0.83 | NPC1 (0.50) | KMT2AGAAALDH1A1MEN1MAPT | |
| SCHEMBL11617967 | 0.82 | KMT2A (0.45) | KMT2AGAAALDH1A1MEN1MAPT | |
| SCHEMBL11618777 | 0.82 | KMT2A (0.49) | KMT2AGAAALDH1A1MEN1MAPT | |
| SCHEMBL11616704 | 0.80 | KMT2A (0.47) | KMT2AGAAALDH1A1MEN1MAPT | |
| SCHEMBL11611124 | 0.80 | NPC1 (0.47) | KMT2AGAAALDH1A1MEN1HPGD | |
| SCHEMBL11615203 | 0.77 | HPGD (0.53) | KMT2AALDH1A1MEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |