Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612952 | 1.00 | LMNA (0.34) | LMNAALDH1A1HTTMGLLSMN1; SMN2 | |
| SCHEMBL11607879 | 0.88 | LMNA (0.32) | LMNA | |
| SCHEMBL11607874 | 0.88 | LMNA (0.32) | LMNA | |
| SCHEMBL11610348 | 0.83 | PHGDH (0.46) | LMNAALDH1A1HTTMGLLSMN1; SMN2 | |
| SCHEMBL11610349 | 0.83 | PHGDH (0.46) | LMNAALDH1A1HTTMGLLSMN1; SMN2 | |
| SCHEMBL11606395 | 0.76 | ALDH1A1 (0.53) | LMNAALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL11606394 | 0.76 | ALDH1A1 (0.53) | LMNAALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9422705 | 0.75 | CYP1A2 (0.54) | LMNAALDH1A1HTTMGLLSMN1; SMN2 | |
| SCHEMBL11605780 | 0.75 | ALDH1A1 (0.39) | LMNAALDH1A1HTTMGLLSMN1; SMN2 | |
| SCHEMBL11608609 | 0.72 | LMNA (0.37) | LMNAALDH1A1HTTMGLLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076814-A | DITHIOCARBAMIC ACID DERIVATIVES | SANKYO COMPANY LIMITED (JA) | 1978-02-28 | — | — | US | disclosed |