Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11663978 | 0.83 | L3MBTL1 (0.41) | PPARGPPARAKDM4EALDH1A1GAA | |
| SCHEMBL11615063 | 0.79 | CNR1 (0.41) | KDM4EMAOBAOC3 | |
| SCHEMBL11611192 | 0.78 | LMNA (0.40) | PPARGPPARAL3MBTL1 | |
| SCHEMBL11517432 | 0.77 | ATM (0.40) | PPARGPPARACETPKDM4EALDH1A1 | |
| SCHEMBL11610243 | 0.76 | PPARG (0.40) | PPARGPPARACETPKDM4EALDH1A1 | |
| SCHEMBL11663126 | 0.75 | KDM4E (0.42) | PPARGPPARAKDM4EALDH1A1GAA | |
| SCHEMBL2737127 | 0.74 | L3MBTL1 (0.47) | PPARGPPARAKDM4EL3MBTL1MAOB | |
| SCHEMBL11613592 | 0.74 | KDM4E (0.49) | PPARGPPARAKDM4EALDH1A1GAA | |
| SCHEMBL8709433 | 0.73 | L3MBTL1 (0.50) | KDM4EALDH1A1L3MBTL1MAOBAOC3 | |
| SCHEMBL11614193 | 0.72 | HTR2A (0.49) | CETPMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122282-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-10-24 | — | — | US | disclosed |
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4085139-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4081478-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-4073808-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |