Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11608156 | 0.95 | CA1 (0.37) | NPC1RAB9ASMN1; SMN2LMNAPTGS1 | |
| SCHEMBL11608396 | 0.84 | PHGDH (0.42) | NPC1RAB9ASMN1; SMN2LMNAPTGS1 | |
| SCHEMBL11607733 | 0.80 | PHGDH (0.41) | NPC1RAB9ASMN1; SMN2LMNAOPRK1 | |
| SCHEMBL11607185 | 0.79 | PHGDH (0.40) | NPC1RAB9ASMN1; SMN2LMNAOPRK1 | |
| SCHEMBL11608809 | 0.78 | ALDH1A1 (0.34) | NPC1RAB9ASMN1; SMN2GAACA1 | |
| SCHEMBL11610581 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8023911 | 0.71 | — | — | |
| SCHEMBL11609558 | 0.69 | MGLL (0.45) | NPC1RAB9ASMN1; SMN2HTTKMT2A | |
| SCHEMBL11608970 | 0.69 | HTT (0.41) | NPC1RAB9ASMN1; SMN2HTTKMT2A | |
| SCHEMBL8009514 | 0.68 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076814-A | DITHIOCARBAMIC ACID DERIVATIVES | SANKYO COMPANY LIMITED (JA) | 1978-02-28 | — | — | US | disclosed |