Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5588137 | 0.87 | ALDH1A1 (0.52) | GABRA1GABRB2ALDH1A1ADAMTS4EGFR | |
| SCHEMBL2642807 | 0.85 | ALB (0.43) | GABRA1GABRB2ALDH1A1HMGB1IDO1 | |
| SCHEMBL15779798 | 0.83 | ALDH1A1 (0.56) | GABRA1GABRB2ALDH1A1EGFRCA1 | |
| SCHEMBL27414080 | 0.78 | HMGB1 (0.62) | ALDH1A1CA1CA2LMNAMMP2 | |
| SCHEMBL29141847 | 0.78 | ERN1 (0.57) | GABRA1GABRB2ALDH1A1CA1CA2 | |
| SCHEMBL2642432 | 0.75 | GABRA1 (0.42) | GABRA1GABRB2CA1CA2CDK2 | |
| SCHEMBL1660262 | 0.74 | — | — | |
| SCHEMBL1538555 | 0.74 | HSPA5 (0.45) | GABRA1GABRB2LMNAHSPA5CYP2D6 | |
| SCHEMBL29712515 | 0.74 | HSPA5 (0.45) | GABRA1GABRB2LMNAHSPA5CYP2D6 | |
| SCHEMBL5588143 | 0.73 | IDO1 (0.37) | GABRA1GABRB2CA1CA2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069340-A | ARYLOXY DIMETHYL IMMONIUM CHLORIDES FROM DIMETHYL FORMAMIDE AND CORRESPONDING ARYL CHLOROFORMATES | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1978-01-17 | — | — | US | disclosed |
| US-3983178-A | Immonium salts and derivatives thereof | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |