Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 3/20 | 0.41 |
| ▸ | EDNRA | P25101 | 3/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11609389 | 0.82 | PTPRC (0.35) | EDNRBEDNRAPTPRCCYP1A2MAPK1 | |
| SCHEMBL8087837 | 0.82 | MEN1 (0.52) | EDNRBEDNRAPTPRCCYP1A2MAPK1 | |
| SCHEMBL8087901 | 0.82 | MEN1 (0.52) | EDNRBEDNRAPTPRCCYP1A2MAPK1 | |
| SCHEMBL11610183 | 0.79 | ALDH1A1 (0.33) | EDNRBEDNRAPTPRCCYP1A2MAPK1 | |
| SCHEMBL3049110 | 0.74 | MAPK1 (0.44) | EDNRBEDNRAPTPRCCYP1A2MAPK1 | |
| SCHEMBL11612293 | 0.70 | PTPRC (0.35) | EDNRBEDNRAPTPRCCYP1A2MAPK1 | |
| SCHEMBL6902840 | 0.69 | MEN1 (0.52) | EDNRBEDNRAPTPRCCYP1A2MAPK1 | |
| SCHEMBL7959774 | 0.69 | MAPK1 (0.44) | EDNRBEDNRAPTPRCCYP1A2MAPK1 | |
| SCHEMBL19164428 | 0.69 | CYP1A2 (0.77) | EDNRBEDNRAPTPRCCYP1A2MAPK1 | |
| SCHEMBL19164165 | 0.69 | MAPK1 (0.62) | EDNRBEDNRAPTPRCCYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4128549-A | Precursors of 4-(1-alkyl-4-piperidylidene-4H-benzo[4,5]cyclohepta-[1,2-b]thiophen-10(9H)-ones | SANDOZ LTD. (CH) | 1978-12-05 | — | — | US | disclosed |
| US-3960894-A | 9-Bromo-or chloro-9,10-dihydro-10-dihydro-10-alkoxy-4H-benzo[4,5]cyclo-hepta[1,2-b]thiophen-4-ones | SANDOZ LTD. (CH) | 1976-06-01 | — | — | US | disclosed |