Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | HPGD | P15428 | 2/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.77 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.55 |
| ▸ | PPARG | P37231 | 4/20 | 0.53 |
| ▸ | RECQL | P46063 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | TOP1 | P11387 | 3/20 | 0.52 |
| ▸ | FABP4 | P15090 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903382 | 1.00 | TRPA1 (0.77) | TRPA1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8903380 | 1.00 | TRPA1 (0.77) | TRPA1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7516435 | 0.89 | TRPA1 (0.62) | TRPA1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8668693 | 0.89 | TRPA1 (0.62) | TRPA1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11806516 | 0.88 | ALDH1A1 (0.98) | TRPA1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL14577648 | 0.88 | TRPA1 (0.72) | TRPA1KMT2AMEN1ALDH1A1LMNA | |
| Prostaglandin A2 SCHEMBL11644837 | 0.87 | ALDH1A1 (1.00) | TRPA1KMT2AMEN1ALDH1A1LMNA | |
| Prostaglandin A2 SCHEMBL11395152 | 0.87 | ALDH1A1 (1.00) | TRPA1KMT2AMEN1ALDH1A1LMNA | |
| Prostaglandin A2 SCHEMBL21670455 | 0.87 | ALDH1A1 (1.00) | TRPA1KMT2AMEN1ALDH1A1LMNA | |
| Prostaglandin A2 SCHEMBL11879316 | 0.87 | ALDH1A1 (1.00) | TRPA1KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179451-A | HYPOTENSIVE, ANTIULCER, BRONCHODILATOR, ANTICONVULSANTS OR ANTIMICROBIAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4107441-A | HYPOTENSIVE, ANTIULCER, BRONCHODILATORS, ANTIMICROBIAL, ANTICONVULSANTS | AMERICAN CYANAMID COMPANY (US) | 1978-08-15 | — | — | US | disclosed |