Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11616947 | 0.91 | PTGDR2 (0.47) | KMT2AMEN1PTGDR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11612692 | 0.90 | MEN1 (0.43) | KMT2AMEN1PTGDR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11615839 | 0.74 | PTGDR2 (0.47) | PTGDR2ALDH1A1SMN1; SMN2GAATP53 | |
| SCHEMBL11617170 | 0.74 | PTGDR2 (0.41) | KMT2AMEN1PTGDR2CCR2ALDH1A1 | |
| SCHEMBL27476563 | 0.73 | SLC16A3 (0.39) | KMT2AMEN1PTGDR2CCR2 | |
| SCHEMBL27486656 | 0.73 | HDAC6 (0.48) | TP53 | |
| SCHEMBL11509390 | 0.72 | GPR139 (0.37) | KMT2AMEN1SMN1; SMN2GAATP53 | |
| SCHEMBL11617121 | 0.72 | PTGDR2 (0.40) | KMT2AMEN1PTGDR2CCR2SMN1; SMN2 | |
| SCHEMBL11616977 | 0.71 | PTGDR2 (0.39) | KMT2AMEN1PTGDR2CCR2ALDH1A1 | |
| SCHEMBL11613797 | 0.70 | RAB9A (0.43) | KMT2APTGDR2CCR2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |