Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | FZD7 | O75084 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9460181 | 0.90 | MAPT (0.69) | MEN1KMT2ALMNAROCK1MAPT | |
| SCHEMBL11611580 | 0.87 | MAPT (0.58) | MEN1KMT2ALMNAROCK1MAPT | |
| SCHEMBL11614626 | 0.85 | CSNK2A1 (0.70) | MEN1KMT2ALMNAROCK1MAPT | |
| SCHEMBL11613436 | 0.81 | MEN1 (0.59) | MEN1KMT2ALMNAROCK1MAPT | |
| SCHEMBL1820221 | 0.80 | NPY5R (0.88) | MEN1KMT2ALMNANPY5RMAPT | |
| SCHEMBL11613685 | 0.79 | MEN1 (0.74) | MEN1KMT2ALMNAMAPTADORA3 | |
| SCHEMBL4743979 | 0.77 | ROCK1 (0.87) | MEN1KMT2ALMNAROCK1MAPT | |
| SCHEMBL3610442 | 0.76 | ALOX5 (0.59) | MEN1KMT2ALMNANPY5RROCK1 | |
| SCHEMBL27259260 | 0.76 | ALDH1A1 (0.78) | MEN1KMT2ALMNAROCK1MAPT | |
| SCHEMBL3603436 | 0.76 | MEN1 (0.61) | MEN1KMT2ALMNAMAPTADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4089965-A | Thiazolylphenylguanidines as antirhinovirus agents | AMERICAN CYANAMID COMPANY (US) | 1978-05-16 | — | — | US | claimed |
| US-4089965-A | Thiazolylphenylguanidines as antirhinovirus agents | AMERICAN CYANAMID COMPANY (US) | 1978-05-16 | — | — | US | disclosed |